Probiotic-loaded microcapsule system for human in situ folate production: Encapsulation and system validation

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• 作者：Philippe E. Ramos^a ; ^{phramos@ceb.uminho.pt} ; Luí ; s Abrunhosa^a ; Ana Pinheiro^a ; ^b ; Miguel A. Cerqueira^c ; Carla Motta^d ; Isabel Castanheira^d ; Maria V. Chandra-Hioe^e ; Jayashree Arcot^e ; José ; A. Teixeira^a ; Antó ; nio A. Vicente^a
• 关键词：5-Methyltetrahydrofolate (PubChem CID ; 444412) ; Folic acid (PubChem CID ; 6037) ; Sodium alginate (PubChem CID ; 5 ; 102 ; 882) ; Chitosan (PubChem CID ; 71853) ; Poly-l-sysine (PubChem CID ; 53628747) ; Tween 80 (PubChem CID ; 5281955) ; Rhodamine B (PubChem CID ; 6694) ; 10-Formyltetrahydrofolate (PubChem CID ; 168809) ; Isothiocynate (PubChem CID ; 16741) ; Carbodiimide hydrochloride (PubChem CID ; 2723939)
• 刊名：Food Research International
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：90
• 期：Complete
• 页码：25-32
• 全文大小：713 K
• 卷排序：90

文摘

Folic acid has inefficient absorption, whilst natural forms have better uptake. Coated microcapsules are able to protect probiotics against the harsh conditions of the stomach. Coated microcapsules are able to exchange nutrients allowing probiotics activation. Coated microcapsules are able to adhere to epithelial cells.