Direct oral anti-coagulants compared with vitamin-K inhibitors and low-molecular-weight-heparin for the prevention of venous thromboembolism in patients with cancer: A meta-analysis study

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• 作者：Natale Daniele Brunetti^a ; ^{natale.brunetti@unifg.it} ; Enrico Gesuete^a ; Luisa De Gennaro^b ; Michele Correale^c ; Pasquale Caldarola^b ; Antonio Gaglione^a ; Matteo Di Biase^a
• 关键词：Direct oral anticoagulants ; Novel oral anticoagulants ; Cancer ; Vitamin-K inhibitors ; Low-molecular-weight-heparin ; Venous thrombo-embolism ; Meta-analysis
• 刊名：International Journal of Cardiology
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：230
• 期：Complete
• 页码：214-221
• 全文大小：507 K
• 卷排序：230

文摘

DOAs seem to be as effective and safe as conventional treatment for the prevention of VTE in patients with cancer when compared with VKI. Higher bleeding rates were found when DOAs are compared with LMWH.