The regulatory α and β subunits of phosphorylase kinase directly interact with its substrate, glycogen phosphorylase

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• 作者：Jackie A. Thompson ; Gerald M. Carlson ; ^{gcarlson@kumc.edu}
• 关键词：Crosslinking ; Phosphorylase kinase ; Glycogen phosphorylase ; Substrate recognition ; Docking sites
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：8 January 2017
• 年：2017
• 卷：482
• 期：2
• 页码：221-225
• 全文大小：682 K
• 卷排序：482

文摘

Two-step crosslinking successfully captured interactions between two large enzymes. Regulatory subunits of phosphorylase kinase directly interact with its substrate. The direct interactions were sensitive to effectors of the kinase.