Copper-catalyzed intramolecular C-N bond formation reaction of 3-amino-2-(2-bromophenyl)dihydroquinazolinones: synthesis of indazolo[3,2-b]quinazolinones
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- 作者：Weiguang Yang ; Leping Ye ; Dayun Huang ; Miaochang Liu ; Jinchang Ding ; Jiuxi Chen ; Huayue Wu
- 关键词：Copper ; Indazolo[3 ; 2-b]quinazolinones ; Intramolecular C&ndash ; N bond formation ; 3-Amino-2-(2-bromophenyl)dihydroquinazolinones
- 刊名：Tetrahedron
- 出版年：2013
- 出版时间：18 November, 2013
- 年：2013
- 卷：69
- 期：46
- 页码：9852-9856
- 全文大小：617 K
文摘
A copper-catalyzed intramolecular C-N bond formation reaction of 3-amino-2-(2-bromophenyl)dihydroquinazolinones has been developed for the synthesis of indazolo[3,2-b]quinazolinones in moderate to good yields. The structure of the newly synthesized indazolo[3,2-b]quinazolinones was unambiguously confirmed by X-ray single-crystal diffraction analysis. Moreover, a possible mechanism for the formation of indazolo[3,2-b]quinazolinones is discussed.