Panusin represents a new family of β-defensin-like peptides in invertebrates

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• 作者：Vivian Montero-Alejo^a ; ^{vivian.montero@fq.uh.cu} ; Gerardo Corzo^b ; Javier Porro-Suardí ; az^a ; Zenia Pardo-Ruiz^a ; Erick Perera^c ; Leandro Rodrí ; guez-Viera^d ; Gabriela Sá ; nchez-Dí ; az^e ; ^f ; Erix Wiliam Herná ; ndez-Rodrí ; guez^e ; ^f ; Carlos Á ; lvarez^g ; Steve Peigneur^h ; Jan Tytgat^h ; Rolando Perdomo-Morales^a ; ^{rolando.perdomo@infomed.sld.cu}
• 关键词：Invertebrate ; Antimicrobial activity ; Secondary structure ; Protein purification ; Membrane binding ; Defensins
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：67
• 期：Complete
• 页码：310-321
• 全文大小：2681 K
• 卷排序：67

文摘

Panusin share the cysteine stabilized α/β motif and is prone to form homodimers. Panusin exerts wide spectrum antimicrobial activity, shows salt insensitive activity and is not hemolytic over human red blood cells. Panusin represent a new family of beta_defensin in invertebrate.