Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for diabetic retinopathy in Japanese patients with type 2 diabetes

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• 作者：Naoto Katakami ; Munehide Matsuhisa ; Hideaki Kaneto ; Taka-aki Matsuoka ; Kenichi Imamura ; Fukashi Ishibashi ; Tsutomu K ; a ; Koichi Kawai ; Takeshi Osonoi ; Atsunori Kashiwagi ; Ryuzo Kawamori ; Iichiro Shimom
• 关键词：Diabetes ; Retinopathy ; Monocyte chemoattractant protein (MCP)-1 ; Polymorphism
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2010
• 出版时间：July 2010
• 年：2010
• 卷：89
• 期：1
• 页码：e9-e12
• 全文大小：178 K

文摘

We examined the association between diabetic retinopathy and monocyte chemoattractant protein (MCP)-1 A-2518G polymorphism in 3802 Japanese type 2 diabetic subjects. The prevalence of diabetic retinopathy was higher as the number of G alleles increased, suggesting that the G allele of this polymorphism is a susceptibility allele for diabetic retinopathy.