Effects of three intravenous lipid emulsions on the survival and mononuclear phagocyte function of septic rats

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• 作者：Garnacho-Montero ; J. ; Ortiz-Leyba ; C. ; Garnacho-Montero ; M.C. ; Garcia-Garmendia ; J.L. ; Pé ; rez-Paredes ; C. ; et. al.
• 关键词：total parenteral nutrition ; lipid emulsion ; bacteremia ; prostaglandin E₂
• 刊名：Nutrition
• 出版年：2002
• 出版时间：September, 2002
• 年：2002
• 卷：18
• 期：9
• 页码：751-754
• 全文大小：46.9 K

文摘

The immunosuppressive effects of intravenous lipid emulsions are a matter of great concern and debate. In a rat model of gram-negative bacteremia, we assessed whether the use of three intravenous lipid emulsions with different triacylglycerol compositions could influence mortality, bacterial clearance, and prostaglandin E₂ (PGE₂) levels and compared these groups with groups of orally fed rats and rats that received a small amount of calories in form of glucose without enteral feeding (starvation).