Identification of CD8 T cell epitopes in VP2 and NS1 proteins of African horse sickness virus in IFNAR(-/-) mice.
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- 作者：Francisco de la Pozaa ; Alejandro Marí ; n-Ló ; peza ; Javier Castillo-Olivaresb ; Eva Calvo-Pinillab ; Javier Ortegoa ; ortego@inia.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：African horse sickness virus ; MVA-VP2 ; MVA-NS1 ; IFNAR(-/-) mice ; CD8+ T cell epitopes
- 刊名：Virus Research
- 出版年：2015
- 出版时间：2 December 2015
- 年：2015
- 卷：210
- 期：Complete
- 页码：149-153
- 全文大小：565 K
文摘
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Two peptides of AHSV-VP2, and one of AHSV-NS1 are identified as CD8+ T cell epitopes.
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These peptides induced the cytotoxicity marker CD107a in CD8+ T cells.
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VP2-1044 and NS1-83 epitopes are conserved among all nine AHSV serotypes.