Differentially proteomic analysis of the Chinese shrimp at WSSV latent and acute infection stages by iTRAQ approach
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- 作者：Shihao Lia ; b ; Fuhua Lia ; b ; fhli@qdio.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Zheng Suna ; Xiaojun Zhanga ; Jianhai Xianga
- 关键词：WSSV ; Proteomics ; iTRAQ ; Fenneropenaeus chinensis ; Latent infection ; Acute infection ; Phagocytosis ; Apoptosis
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：54
- 期：Complete
- 页码：629-638
- 全文大小：1373 K
文摘
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The iTRAQ approach was used to identify differentially expressed proteins in shrimp during WSSV latent and acute infection.
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Many proteins related to cytoskeleton, including myosin, actin, tubulin, and tropomyosin were up-regulated at AI stage.
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The apoptosis process in WSSV AI shrimp seemed to be inhibited as some proteins suppressive on apoptosis were up-regulated.
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83.72% of differentially expressed proteins/genes have a same expression trend between the proteome and transcriptome data.