Short- versus long-duration levofloxacin plus rifampicin for acute staphylococcal prosthetic joint infection managed with implant retention: a randomised clinical trial
详细信息 查看全文
- 作者：Jaime Lora-Tamayo
- 关键词：Biofilm ; Bone and joint infection ; Osteoarticular infection ; Foreign body infection ; Length of therapy
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：48
- 期：3
- 页码：310-316
- 全文大小：592 K
文摘
- •
- <p id="p0010">First randomised trial on the length of therapy in prosthetic joint infection (PJI).p>
- •
- <p id="p0015">Study included staphylococcal PJI treated with levofloxacin plus rifampicin.p>
- •
- <p id="p0020">8 weeks of therapy after debridement for staphylococcal PJI may be sufficient.p>
- •
- <p id="p0025">These results are consistent with those of previous observational studies.p>
- •
- <p id="p0030">Caution may be required in patients with knee PJI and poor evolution.p>