The effect of sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats

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• 作者：S. Charntikov^a ; A.M. Falco^b ; K. Fink^b ; L.P. Dwoskin^c ; R.A. Bevins^b ; ^{rbevins1@unl.edu}
• 关键词：Acetylcholine ; Drug discrimination ; Nicotine dependence ; Interoceptive stimulus ; Pavlovian conditioning ; Smoking ; Tobacco
• 刊名：Neuropharmacology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：113
• 期：part_PA
• 页码：354-366
• 全文大小：1590 K
• 卷排序：113

文摘

Stimulus effects of nicotine were assessed in female and male rats. Nicotine-saline discrimination trained using the discriminated goal-tracking task. Substitution ligands were potential pharmacotherapies or nAChR-binding compounds. Overall, substitution was similar in female and male rats across the tests.