Current knowledge of environmental exposure in children during the sensitive developmental periods

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• 作者：Norma Helena Perlroth^a ; ^b ; ^{norma.perlroth@gmail.com} ; Christina Wyss Castelo Branco^a ; ^c
• 关键词：Children's health ; Environmental exposure ; Vulnerability ; Pathways of toxicity penetration ; Developmental disability
• 刊名：Jornal de Pediatria (Versão em Português)
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：93
• 期：1
• 页码：17-27
• 全文大小：1127 K
• 卷排序：93

文摘

This study aims to identify the scientific evidence on the risks and effects of exposure to environmental contaminants in children during sensitive developmental periods.Data sourceThe search was performed in the Bireme database, using the terms: children's health, environmental exposure, health vulnerability, toxicity pathways and developmental disabilities in the LILACS, MEDLINE and SciELO systems.Data synthesisChildren differ from adults in their unique physiological and behavioral characteristics and the potential exposure to risks caused by several threats in the environment. Exposure to toxic agents is analyzed through toxicokinetic processes in the several systems and organs during the sensitive phases of child development. The caused effects are reflected in the increased prevalence of congenital malformations, diarrhea, asthma, cancer, endocrine and neurological disorders, among others, with negative impacts throughout adult life.ConclusionTo identify the causes and understand the mechanisms involved in the genesis of these diseases is a challenge for science, as there is still a lack of knowledge on children's susceptibility to many environmental contaminants. Prevention policies and more research on child environmental health, improving the recording and surveillance of environmental risks to children's health, should be an ongoing priority in the public health field.