Cytokine mRNA expression in Peromyscus yucatanicus (Rodentia: Cricetidae) infected by Leishmania (Leishmania) mexicana
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- 作者：Elsy Nalleli Loria-Cerveraa ; 1 ; nalleli.cervera@correo.uady.mx" class="auth_mail" title="E-mail the corresponding author ; Erika Ivett Sosa-Bibianoa ; 1 ; erikasosa@correo.uady.mx" class="auth_mail" title="E-mail the corresponding author ; Nicole Raymonde Van Wynsberghea ; 1 ; nvan@correo.uady.mx" class="auth_mail" title="E-mail the corresponding author ; Omar Abdul Saldarriagab ; 1 ; omsaldar@utmb.edu" class="auth_mail" title="E-mail the corresponding author ; Peter C. Melbyb ; 1 ; pcmelby@utmb.edu" class="auth_mail" title="E-mail the corresponding author ; Fernando Jose Andrade-Narvaeza ; 1 ; anarvaez@correo.uady.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：Peromyscus yucatanicus ; Th1/Th2 cytokines ; Leishmania (L.) mexicana ; Clinical infection ; Subclinical infection
- 刊名：Cytokine
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：176-181
- 全文大小：389 K
文摘
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Infection at 4 weeks was characterized by high IFN-γ expression.
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Infection at 12 weeks was characterized by a mixed Th1 and Th2 immune response.
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Clinical course was associated with a specific pattern of cytokines at 12 weeks.
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TNF-α, IL-4, IL-10 and TGF-β could be associated with P. yucatanicus clinical status.