A novel label-free electrochemical immunosensor based on functionalized nitrogen-doped graphene quantum dots for carcinoembryonic antigen detection

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• 作者：Yuying Yang^a ; Qing Liu^a ; ^{qingliu0315@163.com} ; Yan Liu^a ; Jianjian Cui^a ; Hui Liu^a ; Ping Wang^a ; Yueyun Li^a ; Lei Chen^a ; Zengdian Zhao^b ; Yunhui Dong^a ; ^{dyh651118@126.com}
• 关键词：Carcinoembryonic antigen ; Au nanoparticles ; PtPd bimetallic nanoparticles ; Nitrogen-doped graphene quantum dots ; Label-free ; Electrochemical immunosensor
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：31-38
• 全文大小：1499 K
• 卷排序：90

文摘

Nitrogen-doped graphene quantum dots supported PtPd bimetallic nanoparticles was synthesized. The synergetic effect present in PtPd/N-GQDs@Au can increase the electrocatalytic activity towards hydrogen peroxide reduction. The novel PtPd/N-GQDs@Au based immunosensor possesses excellent sensitivity, special selectivity and long-term stability. The strategy provides a great promise in clinical application.