Novel 2-arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: Synthesis and evaluation of their biological activity

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• 作者：Alejandra Salerno^a ; Ana M. Celentano^b ; ^c ; Julieta Ló ; pez^a ; Virginia Lara^a ; Carlos Gaozza^a ; Darí ; o E. Balcazar^d ; Carolina Carrillo^d ; Fernanda M. Frank^b ; ^e ; Marí ; a M. Blanco^a ; ^{mblanco@ffyb.uba.ar}
• 关键词：2-Arylazoimidazoles ; Ultrasound-assisted alkylation ; Chagas' disease ; Biological activity
• 刊名：European Journal of Medicinal Chemistry
• 出版年：2017
• 出版时间：5 January 2017
• 年：2017
• 卷：125
• 期：Complete
• 页码：327-334
• 全文大小：762 K
• 卷排序：125

文摘

Green synthesis of 2-aryazolimidazole derivatives. Ultrasound-assisted alkylation of imidazole. Anti-T. cruzi activity of novel imidazoles.