Research strategies for the treatment of biothreats

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• 作者：John W Cherwonogrodzky
• 刊名：Current Opinion in Pharmacology
• 出版年：2005
• 出版时间：2005
• 年：2005
• 卷：5
• 期：5
• 页码：465-472
• 全文大小：152 K

文摘

Whether it is a layperson in the street or a politician in the Senate, there is widespread fear over the consequences of biothreats. In response to these fears, a wide range of treatments has been developed. These include antibiotics (conventional and unconventional uses), nucleic acids (analogues, antisense, ribozymes and DNAzymes), immunomodulators, antibodies, bacteriophage therapy and micro-encapsulation. Furthermore, there are often additional benefits when these therapeutics are used in combination, rather than alone. Although there has been much investment in therapeutics against a terrorist threat for reasons of national security, there are likely to be far greater benefits and applications on domestic and world health.