Neuregulin-1 and schizophrenia in the genome-wide association study era
详细信息 查看全文
- 作者：Md Shaki Mostaida ; David Lloydc ; i ; j ; Benny Liberga ; Suresh Sundramb ; d ; h ; Avril Pereirab ; Christos Pantelisa ; b ; Tim Karlc ; g ; Cynthia Shannon Weickertc ; i ; j ; Ian P. Everalla ; b ; d ; Chad A. Bousmana ; b ; e ; f ; cbousman@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Neuregulin 1 ; Schizophrenia ; Psychosis ; Excitatory neurotransmission ; Inhibitory neurotransmission ; Neuroimaging ; Genotype ; Transcript
- 刊名：Neuroscience & Biobehavioral Reviews
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：387-409
- 全文大小：2524 K
文摘
- •
We assess NRG1’s relevance to schizophrenia in the GWAS era.
- •
The past decade of clinical research on NRG1 and schizophrenia is summarized.
- •
We review preclinical work on NRG1’s role in excitatory/inhibitory neurotransmission.
- •
We propose a strategy forward for future NRG1 research in schizophrenia.