A study involving paired case-control to illustrate the prevalence of SAFV and AiV. AiV and SAFV in stools from children were more prevalent in controls than cases. Estimated the viral loads of AiV and SAFV in stool samples from pediatric cases with diarrhea and healthy controls. Provided the evidence of no association of SAFV and AiV in acute gastroenteritis in children. Reported the major genotype of AiV and SAFV in China.