Characterization of bovine A20 gene: Expression mediated by NF-κB pathway in MDBK cells infected with bovine viral diarrhea virus-1
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- 作者：Fernanda Fredericksen ; Melina Villalba ; Ví ; ctor H. Olavarrí ; a ; volavarria@uach.cl" class="auth_mail" title="E-mail the corresponding author
- 关键词：AP-1 ; activator protein 1 ; AREs ; adenylate- and uridylate-rich (AU-rich) elements ; bp ; base pair ; Bcl10 ; B-cell lymphoma 10-encoded protein ; Bcl3 ; B-cell lymphoma 3-encoded protein ; BVDV-1 ; bovine viral diarrhea virus ; CBP ; CREB-binding protein ; DUBs ; deubiquitinating enzymes ; HAUSP ; herpesvirus-associated ubiquitin-specific protease ; hpi ; hours post-infection ; IKK ; inhibitor of κB (IκB) kinase ; IRF3 ; interferon regulatory factor 3 ; kb ; kilobase pair ; MDBK ; Madin-Darby bovine kidney ; MOI ; multip
- 刊名：Gene
- 出版年：2016
- 出版时间：1 May 2016
- 年：2016
- 卷：581
- 期：2
- 页码：117-129
- 全文大小：2259 K
文摘
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A20 is a key regulatory factor in the immune response.
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BVDV-1 stimulates the expression of A20 regulated by NF-қB.
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Bovine A20 mRNA had a half-life of only 32 min.