The geological settings, geological characteristics, metallogenic and ore potentialities of the Takati lead-zinc deposit were discussed. The Takati lead-zinc deposit is located in the potentiality zone of the Tamukalangu Pb-Zn-Cu ore belt in west Kunlun and is controlled by the west Kunlun tectonic belt and Kangxiwa tectonic belt. The orebodies occur in the strata or the vein. The orebodies are controlled by the dolomite sandstone exposed layer and the inter-formational zones. Wall rock is made up of altered dolostone and clastic sandstone. The ore minerals include galena and sphalerite and the ore types are similar to MVT. The potential resources are huge, especially for lead-zinc deposit. So the potentiality of ore is great.