Yanling-Lanshan fault is a abyssal fault belt with a long activity time and large scale in south Hunan. It plays an important role to control the forming and distribution of regional ore fields. It controls the forming and distribution of W, Sn, Pb and Zn polymetalic ore belt in NE direction in Yanling-Lanshan region. On the basis of the study of geophysical setting, geochemical feature, sedimentary lithofacies formation, structural and magmatic process and mineralization characteristics, the authors have proposed the exploration thought of two prospecting targets in landscape direction and the second mine space in the deep area.