The Hongtoushan Archean Cu-Zn Massive Sulfide Deposit (MSD), which was metamorphosed (3. 0~2. 8 Ga) to upper amphibolite facies at temperatures between 600℃ and 650℃, occurs in the Hunbei granite-greenstone terrane, Liaoning Province. Whole-rock geochemical analyses indicate that the semiconformable CAG was derived ultimately from five kinds of lithology (basalts, basaltic andesites, andesites, dacites, and rhyolites), whereas the pipe-like CAG from a single lithology (rhyolites). Stratiform CAG could be used to evaluate mineralization potential of VMS in metamorphic terranes, while discordant CAG containing sulfide-bearing quartz veins could serve as a good indictor for overlying stratiform massive sulfide ores as well as an exploration target itself.